Research Grant History

 

1998 CND Grant Recipients

  • "Psychodermatology of selected nail disease:Onychomycosis and brittle nail syndrome," M Alam, MD, Columbia Univ College of Physicians and Surgeons
  • "Innate defense of nails," RL Gallo, MD,PhD, Boston Children's Hospital
  • "Roles of En1, Wnt7a and Lmx1b in nail development," CA Loomis, MD, PhD, NYU Medical School
  • "Nail diseases: Search for mouse/human analogues," JP Sundberg, DVM, PhD, The Jackson Laboratory
  • "Comparison of diagnostic methods in the evaluation of onychomycosis," JM, Weinberg, MD, NY Medical College-Metropolitan Hospital Center

2000 CND Grant Recipients

  • "Innate defense of nails," RL Gallo, MD,PhD, Boston Children's Hospital
  • "Roles of En1, Wnt7a, Lmx1b in nail development," CA Loomis, MD, PhD, NYU Medical School
  • "Mouse models for nail disorders," JP Sundberg, DVM, PhD, The Jackson Laboratory

2003 CND Grant Recipients

  •  “Cells involved in human digit tip regeneration,” Christopher Allan, MD, University of Washington School of Medicine

2004 CND Grant Recipients

  •  “Investigator Initiated Study to Examine the Relationship Between Water Content of the Human Nail Plate and Clinically Brittle Nails,” Dana Stern, MD, PhD, Dept Dermatology, Mt Sinai School of Medicine
  • “Clinical versus Laboratory Presence of Onychomycosis,” George Wallace, DPM, MBA, University of Medicine and Dentistry of New Jersey
  • “Occult Onychomycosis Complicating Tinea Pedis Infection,” Hobart Walling, MD, PhD, Dept Dermatology, University of Iowa Hospitals and Clinics

2005 CND Grant Recipients

  •  “The Prevalence of Onychodystrophy and its Relationship to Diabetic Foot Infection,” David G. Armstrong, DPM, Dr William M. Scholl College of Podiatric Medicine at Rosalind Franklin University

2006 CND Grant Recipients

  •  “The Relationship Between Rate of Dehydration of the Nail Plate and Clincially Brittle Nails,” Caroline Halverstam, MD, Dept of Dermatology, Mt Sinai School of Medicine
  • “Videodermoscopy in nail psoriasis and inflammatory nail disorders,” Matilde Iorizzo, MD, Dept of Dermatology, University of Bologna
  • “Characterization of Nails in Mouse Mutants with Hair Abnormalities,” John P. Sundberg, DVM, PhD, The Jackson Laboratory

2007 CND Grant Recipients

  • “Defining the role of keratin 6 in nail diseases by using mutant mouse models,” Jiang Chen, PhD, University of Colorado
  • “A novel method of cytology to aid in diagnosis of psoriatic fingernail pathology,” Erin Moore, MD, University of Washington

2011 CND Grant Recipients

  • “Nail clipping can be used to diagnose nail psoriasis,” Mariya Miteva, MD, University of Miami

2013 CND Grant Recipients

  • “The functional study of onychodermis (specialized nail mesenchyme) in nail morphogenesis,” Dong-Youn Lee, MD, Samsung Medical Center, Seoul, South Korea
  • “The Molecular and Biological Basis for witch nails (whnl),” C. Herbert Pratt, PhD, The Jackson Laboratory

2014 Grant Recipients

  • “Gene expression analysis of the human nail unit,” Julie Jefferson, MD, Dermatology Department, Johns Hopkins University

 

Publications Acknowledging CND Support

M. Alam, M. Moossavi, I. Ginsburg, and R. K. Scher. A psychometric study of patients with nail dystrophies. J.Am Acad.Dermatol 45 (6):851-856, 2001.

R. A. Dorschner, B. Lopez-Garcia, J. Massie, C. Kim, and R. L. Gallo. Innate immune defense of the nail unit by antimicrobial peptides. J.Am.Acad.Dermatol. 50 (3):343-348, 2004.

K. J. McElwee, D. Boggess, J. Miller, L. E. King, Jr., and J. P. Sundberg. Spontaneous alopecia areata-like hair loss in one congenic and seven inbred laboratory mouse strains. J.Investig.Dermatol Symp.Proc. 4 (3):202-206, 1999.

A. A. Panteleyev, A. M. Christiano, T. G. O'Brien, and J. P. Sundberg. Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions. Exp.Dermatol. 9 (2):146-151, 2000.

R. B. Presland, D. Boggess, S. P. Lewis, C. Hull, P. Fleckman, and J. P. Sundberg. Loss of Normal Profilaggrin and Filaggrin in Flaky Tail (ft/ft) Mice: an Animal Model for the Filaggrin-Deficient Skin Disease Ichthyosis Vulgaris. J.Invest.Dermatol. 115 (6):1072-1081, 2000.

J. P. Sundberg, D. Boggess, C. Bascom, B. J. Limberg, L. D. Shultz, B. A. Sundberg, L. E. King, Jr., and X. Montagutelli. Lanceolate hair-J (lahJ): a mouse model for human hair disorders. Exp.Dermatol 9 (3):206-218, 2000.

J. P. Sundberg and L. E. King, Jr. Skin and its appendages: Normal anatomy and pathology of spontaneous, transgenic, and targeted mouse mutations. In: Pathology of Genetically Engineered Mice, edited by J. Ward, J. F. Mahler, R. R. Maronpot, and J. P. Sundberg, Ames, IA.:Iowa State University Press, 2000, p. 183-215.

J. P. Sundberg, D. Boggess, B. A. Sundberg, K. Eilertsen, S. Parimoo, M. Filippi, and K. Stenn. Asebia-2J (Scd1ab2J): a new allele and a model for scarring alopecia. Am.J.Pathol. 156 (6):2067-2075, 2000.

J. P. Sundberg and L. E. King, Jr. Morphology of hair in normal and mutant laboratory mice. Eur.J.Dermatol. 11 (4):357-361, 2001.

V. A. Randall, J. P. Sundberg, and M. P. Philpott. Animal and in vitro models for the study of hair follicles. J.Investig.Dermatol.Symp.Proc. 8 (1):39-45, 2003.

J. P. Sundberg and L. E. King, Jr. Mouse alopecia areata models: an array of data on mechanisms and genetics. J.Investig.Dermatol.Symp.Proc. 8 (2):173-175, 2003.

L. Mecklenburg, R. Paus, Z. Halata, L. S. Bechtold, P. Fleckman, and J. P. Sundberg. FOXN1 is critical for onycholemmal terminal differentiation in nude (Foxn1) mice. J.Invest Dermatol. 123 (6):1001-1011, 2004.

R. E. Seymour, T. Ichiki, I. Mikaelian, D. Boggess, K. A. Silva, and J. P. Sundberg. Necropsy Methods. In: Handbook of Experimental Animals: The Laboratory Mouse, edited by H. J. Hedrich, London:Academic Press, 2004, p. 495-516.

L. E. King, K. J. McElwee, and J. P. Sundberg. Alopecia Areata. In: Dermatologic Immunity, edited by B. Nickoloff and F. O. Nestle, Basel:Karger, 2008, p. 280-312.

J. Sun, K. A. Silva, K. J. McElwee, L. E. King, Jr., and J. P. Sundberg. The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results. Exp.Dermatol. 17 (10):793-805, 2008.

P. Fleckman, K. Jaeger, K. A. Silva, and J. P. Sundberg. Comparative anatomy of mouse and human nail units. Anat.Rec.(Hoboken.) 296 (3):521-532, 2013.

J. M. Weinberg, E. K. Koestenblatt, W. D. Tutrone, H. R. Tishler, and L. Najarian. Comparison of diagnostic methods in the evaluation of onychomycosis. J.Am.Acad.Dermatol. 49 (2):193-197, 2003.

Allan CH, Fleckman P, Fernandes RJ, Hager B, James J, Wisecarver Z, Satterstrom FK, Norman A, Pirrone A, Rubin BP, Zhang M, Ramay HR, Clark JM. Human fetal digit response to tip amputation in vitro. In Press, Wound Repair and Regeneration, 2006.

D. K. Stern, S. Diamantis, E. Smith, H. Wei, M. Gordon, W. Muigai, E. Moshier, M. Lebwohl, and P. Spuls. Water content and other aspects of brittle versus normal fingernails. J.Am.Acad.Dermatol. 57 (1):31-36, 2007.

H. W. Walling. Subclinical onychomycosis is associated with tinea pedis. Br.J.Dermatol., 2009.

M. Iorizzo, M. Dahdah, C. Vincenzi, and A. Tosti. Videodermoscopy of the hyponychium in nail bed psoriasis. J.Am.Acad.Dermatol. 58 (4):714-715, 2008.

J. Chen, K. Jaeger, Z. Den, P. J. Koch, J. P. Sundberg, and D. R. Roop. Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling
pachyonychia congenita. J.Invest Dermatol. 128 (2):270-279, 2008.

Chen J, Roop DR: Genetically engineered mouse models for skin research: taking the next step. J Dermatol Sci 52 (1): 1-12, 2008.

 
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